8805/3 Undifferentiated sarcoma


Definitions

Cervix uteri
ICD-O-3 topography code: C53
ICD10: C53
           

Undifferentiated endocervical sarcomas are polypoid or infiltrative tumours lacking specific differentiation. The neoplastic cells are spindle- or stellate-shaped and characterized by ill defined borders, scanty cytoplasm, hyperchromatic nuclei, nuclear atypia, and a markedly increased mitotic activity. They are arranged in a sheet-like, fasciculated or storiform pattern. The tumour contains areas of haemorrhage, necrosis, and myxoid degeneration.
Undifferentiated endocervical sarcomas affect adults. Patients typically present with vaginal bleeding or discharge. The prognosis is poor1
 
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



.



Vagina
ICD-O-3 topography code: C52
ICD10: C52
           

A sarcoma with an infiltrating pattern composed of small spindle-shaped cells lacking specific features.



Ovary
ICD-O-3 topography code: C56
ICD10: C56
           

A sarcoma with an infiltrating pattern composed of small spindle-shaped cells lacking specific features.



Connective, subcutaneous and other soft tissues
ICD-O-3 topography code: C49
ICD10: C49
           

A sarcoma with an infiltrating pattern composed of small spindle-shaped cells lacking specific features.