8032/3 Spindle cell carcinoma, NOS


Definitions

Bronchus and lung
ICD-O-3 topography code: C34
ICD10: C34
           

Spindle cell carcinoma is a malignant epithelial neoplasm of bronchus and lung histologically characterized by anaplasia and the presence of spindle cells. Giant cells and a sarcomatous component may also be present.



Colon and rectum
ICD-O-3 topography code: C18-C20
ICD10: C18-C20
           

Spindle cell carcinoma is a malignant epithelial neoplasm of bronchus and lung histologically characterized by anaplasia and the presence of spindle cells. Giant cells and a sarcomatous component may also be present.

Spindle cell carcinoma of the colon and rectum
This is a biphasic carcinoma with a spindle- cell sarcomatoid component in which the tumour cells are at least focally immunoreactive for keratins 1
Click to access Pubmed
Aramendi T, Fernández-Aceñero MJ, Villanueva MC (2003)
Carcinosarcoma of the colon: report of a rare tumor.
Pathol Res Pract 199: 345-8



2
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Jeong YJ, Lee MR, Kim JC, Hwang PH, Moon WS, Chung MJ (2008)
Carcinosarcoma of the rectosigmoid colon in a 13-year-old girl.
Pathol Int 58: 445-50



3
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Kim JH, Moon WS, Kang MJ, Park MJ, Lee DG (2001)
Sarcomatoid carcinoma of the colon: a case report.
J Korean Med Sci 16: 657-60



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Breast
ICD-O-3 topography code: C50
ICD10: C50
           

Spindle cell carcinoma belongs to the 'Metaplastic carcinomas' group of tumours.

Spindle cell carcinomas are characterized by atypical spindle cells, arranged in a multitude of architectural patterns ranging from long fascicles in herringbone or interwoven patterns to short fascicles in a storiform (?cartwheel?) patterns
4
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Carter MR, Hornick JL, Lester S, Fletcher CD (2006)
Spindle cell (sarcomatoid) carcinoma of the breast: a clinicopathologic and immunohistochemical analysis of 29 cases.
Am J Surg Pathol 30: 300-9



5
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Gersell DJ, Katzenstein AL (1981)
Spindle cell carcinoma of the breast. A clinocopathologic and ultrastructural study.
Hum Pathol 12: 550-61



6
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Wargotz ES, Deos PH, Norris HJ (1989)
Metaplastic carcinomas of the breast. II. Spindle cell carcinoma.
Hum Pathol 20: 732-40



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See Metaplastic carcinoma of no special type for general discussion on metaplastic breast carcinomas.