8370/0 Adrenal cortical adenoma, NOS
Synonyms
Adrenal cortical tumor, benignAdrenal cortical tumor, NOS
Definitions
Adrenal gland | ||
ICD-O-3 topography code: | C74 |
Adrenal cortical adenoma is a benign epithelial neoplasm of the adrenal cortical layers. It can be associated with the overproduction of glucocorticoids (Cushing syndrome), androgenic or estrogenic steroids (adrenogenital syndrome), or mineralocorticoids (Conn syndrome)1
Sternberg's Diagnostic Surgical Pathology
4th Edition
Lippincott, Williams & Wilkins: Philadelphia 2004
Histologically, the presence of severe cortical atrophy in adjacent non-neoplastic adrenal glands reflects significant suppression of the hypothalamic-pituitary-adrenal axis. These patients may need glucocorticoid supplementation 2
Click to access Pubmed |
Immunolocalization of dehydroepiandrosterone sulfotransferase in normal and pathologic human adrenal gland.
Mod Pathol 8: 891-6
The true incidence of adrenal cortical adenomas is unknown. Nodules are found commonly at autopsy and are more common with increasing age and with vascular diseases 3
World Health Organization Classification of Tumours. Pathology and Genetics of Tumors of Endocrine Organs
IARC Press: Lyon 2004