8336/0 Hyalinizing trabecular adenoma


Definitions

Thyroid gland
ICD-O-3 topography code: C73

A rare, circumscribed or encapsulated tumor arising from the follicular cells of the thyroid gland, histologically characterized by a trabecular growth pattern and hyalinized stroma.

Hyalinizing trabecular adenoma of the thyroid gland is unusual under the age of 30 years and is about equally distributed in the fourth through the seventh decades with a mean age of 47 years. There is a marked female predilection 1
 
Ronald A. DeLellis, Ricardo V. Lloyd, Philipp U. Heitz, Charis Eng
World Health Organization Classification of Tumours. Pathology and Genetics of Tumors of Endocrine Organs
IARC Press: Lyon 2004



. The vast majority of cases have a benign clinical course. The etiology of this neoplasm is unknown; some cases have occurred following radiation exposure 2
 
Ronald A. DeLellis, Ricardo V. Lloyd, Philipp U. Heitz, Charis Eng
World Health Organization Classification of Tumours. Pathology and Genetics of Tumors of Endocrine Organs
IARC Press: Lyon 2004