9801/3 Acute leukemia, NOS


Blast cell leukemia
Stem cell leukemia
Undifferentiated leukaemia


Tumours of haematopoietic and lymphoid tissues
ICD-O-3 topography code: C42 and C77
ICD10: C95.0

/span>cute undifferentiated leukaemia expresses no markers considered specific for either lymphoid or myeloid lineage. Before categorizing a leukaemia as undifferentiated, it is necessary to perform immunophenotyping with a comprehensive panel of monoclonal antibodies in order to exclude leukaemias of unusual lineages, such as those derived from myeloid or plasmacytoid dendritic cell precursors, NK-cell precursors, basophils or even non-haematopoietic tumours.