9420/3 Fibrillary astrocytoma


Fibrous astrocytoma


Tumours of the central nervous system
ICD-O-3 topography code: C70, C71 and C72
ICD10: C71

The most frequent histological variant of diffuse astrocytoma WHO grade II. It is predominantly composed of fibrillary neoplastic astrocytes. Nuclear atypia is a diagnostic criterion but mitotic activity, necrosis and microvascular proliferation are absent. The occasional or regional occurrence of gemistocytic neoplastic cells is compatible with the diagnosis of fibrillary astrocytoma 1
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (Eds.)
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007