8262/3 Villous adenocarcinoma


Definitions

Cervix uteri
ICD-O-3 topography code: C53
ICD10: C53
           

Villous adenocarcinoma of the cervix is a variant of mucinous adenocarcinoma characterized by a frond-like pattern. The papillae and glands are typically lined by one to several layers of columnar cells, some of which contain mucin. The epithelium is usually moderately to well differentiated. There are scattered mitoses. The invasive part of the tumour typically consists of elongated branching glands separated by fibrous stroma.
Cervical villous adenocarcinoma generally arises in young women. Lymph node metastasis is rare1
 
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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Corpus uteri
ICD-O-3 topography code: C54
ICD10: C54
           

Villous adenocarcinoma is a variant of endometrioid adenocarcinoma characterized by numerous villous fronds with delicate central cores. The villoglandular elements usually involve only a part of a low-grade endometrioid carcinoma and not the entire tumour
2
 
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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