9250/3 Giant cell tumor of bone, malignant


Osteoblastoma, malignant
Giant cell sarcoma of bone


ICD-O-3 topography code: C40-C41
ICD10: C40-C41

A high grade aggressive bone tumor, usually arising in the end of long bones. The tumor is composed of round or oval mononuclear cells, uniformly distributed osteoclast-like giant cells, and a sarcomatous spindle cell component. Clinical presentation includes pain and edema in the affected area.