9103/0 Partial hydatidiform mole


Corpus uteri
ICD-O-3 topography code: C54

A partial hydatidiform mole is a variant of hydatidiform mole characterized by the presence of two populations of chorionic villi: one population of normal size and the other with hydropic changes. Typical features are minimal trophoblastic hyperplasia, enlarged and cavitated villi, as well as villi with scalloped borders, which often contain trophoblastic inclusions. Nucleated fetal red blood cells are frequently found within stromal blood vessel. The karyotype is typically triploid (>90% of cases), resulting from the fertilization of an ovum by two sperms. Fetuses identified with partial moles usually have stigmata of triploidy including multiple congenital anomalies and growth retardation1
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003