9080/1 Solid teratoma


Related terms

Teratoma, NOS

Definitions

Tumours of the central nervous system
ICD-O-3 topography code: C70, C71 and C72

A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach. According to the level of differentiation of the tissues which comprise the tumor, they are classified as mature teratoma or immature teratoma.

Teratoma with malignant transformation is characterized by malignancy and an aggressive clinical course.



Liver and intrahepatic bile ducts
ICD-O-3 topography code: C22

A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach. According to the level of differentiation of the tissues which comprise the tumor, they are classified as mature teratoma or immature teratoma.



Adrenal gland
ICD-O-3 topography code: C74

Teratoma is a non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach. According to the level of differentiation of the tissues which comprise the tumor, they are classified as mature teratoma or immature teratoma.



Thyroid gland
ICD-O-3 topography code: C73

A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach. According to the level of differentiation of the tissues which comprise the tumor, they are classified as mature teratoma or immature teratoma.

There are approximately 300 cases of thyroid teratomas reported, representing less than 0.1% of all thyroid gland neoplasms. Approximately 50% of cases manifest in newborns; occurrence in adults is very unusual 1
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Grosfeld JL, Ballantine TV, Lowe D, Baehner RL (1976)
Benign and malignant teratomas in children: analysis of 85 patients.
Surgery 80: 297-305



2
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Jordan RB, Gauderer MW (1988)
Cervical teratomas: an analysis. Literature review and proposed classification.
J Pediatr Surg 23: 583-91



3
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Tapper D, Lack EE (1983)
Teratomas in infancy and childhood. A 54-year experience at the Children's Hospital Medical Center.
Ann Surg 198: 398-410



. There is generally no gender predilection, though malignant teratomas may occur more frequently in males 4
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Thompson LD, Rosai J, Heffess CS (2000)
Primary thyroid teratomas: a clinicopathologic study of 30 cases.
Cancer 88: 1149-58



. Among neonates and infants, there is a near absence of malignant behaviour, but thyroid teratomas can cause significant morbidity due to respiratory distress or the presence of associated malformation of vital structures in the neck 5
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Kooijman CD (1988)
Immature teratomas in children.
Histopathology 12: 491-502



6
Click to access Pubmed
Thompson LD, Rosai J, Heffess CS (2000)
Primary thyroid teratomas: a clinicopathologic study of 30 cases.
Cancer 88: 1149-58



.



Fallopian tube and Uterine ligaments
ICD-O-3 topography code: C57

A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach. According to the level of differentiation of the tissues which comprise the tumor, they are classified as mature teratoma or immature teratoma.



Kidney
ICD-O-3 topography code: C64

Teratoma is a non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis
7
 
Eble JE, Sauter G, Epstein JI, Sesterhenn IA (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs.
3rd Edition
IARC Press: Lyon 2004



, ovary 8
 
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



, and extragonadal sites including central nervous system, mediastinum, lung, and stomach. According to the level of differentiation of the tissues which comprise the tumor, they are classified as mature teratoma or immature teratoma.

Reports of teratomas of the kidney are very rare. Reported cases involved the renal parenchyma or the renal hilus and have been indistinguishable from teratomas of the gonads
9
 
Eble JE, Sauter G, Epstein JI, Sesterhenn IA (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs.
3rd Edition
IARC Press: Lyon 2004



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