8898/1 Metastasizing leiomyoma


Corpus uteri
ICD-O-3 topography code: C54

Benign metastasizing leiomyoma is an ill defined condition characterized by histologically benign metastatic smooth muscle tumour deposits in lungs, abdomen or lymph nodes that appear to be derived from a benign uterine leiomyoma1
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Esteban JM, Allen WM, Schaerf RH (1999)
Benign metastasizing leiomyoma of the uterus: histologic and immunohistochemical characterization of primary and metastatic lesions.
Arch Pathol Lab Med 123: 960-2

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Tietze L, Günther K, Hörbe A, Pawlik C, Klosterhalfen B, Handt S, Merkelbach-Bruse S (2000)
Benign metastasizing leiomyoma: a cytogenetically balanced but clonal disease.
Hum Pathol 31: 126-8

. Almost all cases have been reported in women with a history of pelvic surgery. Most examples of "benign metastasizing leiomyoma", however, appear to be either a primary benign smooth muscle lesion of the lung in a woman with a history of uterine leiomyoma or pulmonary metastases from a histologically non-informative smooth muscle tumour of the uterus3
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003