8503/0 Ductal papilloma



Definitions

Breast
ICD-O-3 topography code: C50

Intraductal papillomas are benign lesions that are characterized by finger-like fibrovascular cores covered by an epithelial and myoepithelial cell layer. They are broadly divided into two groups: central (solitary) and peripheral (multiple) 1
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Ohuchi N, Abe R, Takahashi T, Tezuka F (1984)
Origin and extension of intraductal papillomas of the breast: a three-dimensional reconstruction study.
Breast Cancer Res Treat 4: 117-28



. Central papillomas originate in the large ducts, usually of the subareolar region without involving the terminal-duct lobular unit (TDLU), whereas peripheral papillomas always have their roots in the TDLU, even if they extend into the ducts.






Lip, Oral Cavity and Oropharynx
ICD-O-3 topography code: C00-C06, C09-C10, C14

An intraluminal papillary epithelial neoplasm arising within the ducts. Representative examples are the intraductal breast papilloma and the salivary gland intraductal papilloma.



Salivary glands
ICD-O-3 topography code: C07-C08

An intraluminal papillary epithelial neoplasm arising within the ducts. Representative examples are the intraductal breast papilloma and the salivary gland intraductal papilloma.