8406/0 Syringocystadenoma papilliferum


Related terms

Papillary syringadenoma

Definitions

Salivary glands
ICD-O-3 topography code: C07-C08

A benign adnexal neoplasm occurring during childhood or adolescence. It usually presents as a papular lesion or a plaque on the head and neck. It may arise in an organoid nevus such as sebaceous. It is characterized by an endophytic invagination of the epithelium into the dermis. There are dermal cystic spaces present, containing villous projections. Complete excision is curative.



Skin
ICD-O-3 topography code: C44

Syringoadenoma (syringocystadenoma papilliferum) is a benign adnexal neoplasm characterized by endophytic invaginations of epithelium into the dermis. Cystic spaces within the dermis contain villous projections. Luminal cells frequently display decapitation secretion. The stroma contains numerous plasma cells. Most syringoadenomas arise in the head and neck area and typically present as one or more warty papules or as a solitary grey or red plaque.
Syringoadenoma is a tumour of childhood and adolescence. At least one third of cases arise in association with an organoid nevus such as nevus sebaceous. Complete excision is curative1
 
LeBoit PE, Burg G, Weedon D, Sarasin A (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours
3rd Edition
IARC Press: Lyon 2005



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