8316/3 Cyst-associated renal cell carcinoma


ICD-O-3 topography code: C64
ICD10: C64

This diagnostic term refers to a rare type of renal cell carcinoma presenting as well-circumscribed multicystic mass without solid areas. The inner lining of the cystic structures is composed of clear cells.
Cyst-associated renal cell carcinoma CRCC has been reported to amount to 3.5% of renal cell carcinomas and to have a relatively favourable prognosis 1
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Onishi T, Oishi Y, Goto H, Tomita M, Abe K, Sugaya S (2001)
Cyst-associated renal cell carcinoma: clinicopathologic characteristics and evaluation of prognosis in 27 cases.
Int J Urol 8: 268-74

. Preoperative diagnosis of cyst-associated RCC is very difficult, especially in cases of RCC originating in a cyst 2
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Kim KA, Choi JW, Park CM, Lee CH, Lee JH, Yoon DK, Seol HY (2006)
Unusual renal cell carcinomas: a pictorial essay.
Abdom Imaging 31: 154-63


Cyst-associated renal cell carcinoma is ot contained in the 2004 WHO Classification of renal cell carcinomas
Eble JE, Sauter G, Epstein JI, Sesterhenn IA (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs.
3rd Edition
IARC Press: Lyon 2004

and largely synonymous with multilocular cystic renal cell carcinoma.