8075/3 Squamous cell carcinoma, adenoid


Synonyms

Squamous cell carcinoma, pseudoglandular
Squamous cell carcinoma, acantholytic

Definitions

Skin
ICD-O-3 topography code: C44
ICD10: C44
           

Acantholytic squamous cell carcinoma (ASCC) is a variant of squamous cell carcinoma (SCC)characterized by a loosening of the intercellular bridges, resulting in acantholysis. These tumours may present as intraepidermal (in-situ) or invasive SCC 1
 
LeBoit PE, Burg G, Weedon D, Sarasin A (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours
3rd Edition
IARC Press: Lyon 2005



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ASCC develops on sun-exposed skin, predominantly in the head and neck region, in particular on and around the ears. The lesions present as slowly growing scaly and occasionally ulcerated papules or plaques. Areas of acantholysis may produce large intra-epidermal cavities which may extend to adjacent follicular structures.
Adenoid squamous cell carcinoma usually affects elderly individuals with a male predominance. The most important etiologic risk factor is UV-B radiation. The clinical course of ASCC is dependent on the size and depth of the lesion
2
 
LeBoit PE, Burg G, Weedon D, Sarasin A (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours
3rd Edition
IARC Press: Lyon 2005



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Lip, Oral Cavity and Oropharynx
ICD-O-3 topography code: C00-C06, C09-C10, C14
ICD10: C00-C06, C09-C10, C14
           

A squamous cell carcinoma characterized by the formation of gland-like structures.



Hypopharynx, Larynx and Trachea
ICD-O-3 topography code: C13, C32, C33
ICD10: C13, C32, C33
           

A squamous cell carcinoma characterized by the formation of gland-like structures.



Nasal cavity and Sinuses
ICD-O-3 topography code: C30-C31
ICD10: C30-C31
           

A squamous cell carcinoma characterized by the formation of gland-like structures.