9871/3 Acute myeloid leukemia with abnormal marrow eosinophils


Synonyms

Acute myeloid leukemia, t(16;16)(p 13;q 11)
Acute myeloid leukemia, CBF-beta/MYH11
Acute myelomonocytic leukemia with abnormal eosinophils
FAB M4Eo
Acute myeloid leukaemia, inv(16)(p13;q22)

Definitions

Tumours of haematopoietic and lymphoid tissues
ICD-O-3 topography code: C42 and C77
ICD10: C92.7
           

/span>cute myeloid leukaemia with inv(16) (p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11 is an AML that usually shows monocytic and granulocytic differentiation and characteristically abnormal eosinophil component in the BM {a8700}1
Click to access Pubmed
Marlton P, Keating M, Kantarjian H, Pierce S, O'Brien S, Freireich EJ, Estey E (1995)
Cytogenetic and clinical correlates in AML patients with abnormalities of chromosome 16.
Leukemia 9: 965-71



2
Click to access Pubmed
Speck NA, Gilliland DG (2002)
Core-binding factors in haematopoiesis and leukaemia.
Nat Rev Cancer 2: 502-13



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