9716/3 Hepatosplenic γδ (gamma-delta) cell lymphoma


Definitions

Liver and intrahepatic bile ducts
ICD-O-3 topography code: C22
ICD10: C86.1
           

Hepatosplenic T-cell lymphoma (HSTL) is an aggressive extranodal and systemic neoplasm derived from cytotoxic T-cells, usually of γδ T-cell receptor type. It is typically composed of medium-sized lymphoid cells with marked sinusoidal infiltration of spleen, liver and bone marrow (BM) 1
 
Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (Eds.)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
4th Edition
International Agency for Research on Cancer: Lyon 2008



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Tumours of haematopoietic and lymphoid tissues
ICD-O-3 topography code: C42 and C77
ICD10: C86.1
           

/span>epatosplenic T-cell lymphoma (HSTL) is an extranodal and systemic neoplasm derived from cytotoxic T-cells usually of γδ T-cell receptor type. It is usually composed of medium-sized lymphoid cells, demonstrating marked sinusoidal infiltration of spleen, liver and bone marrow (BM).

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