9441/3 Giant cell glioblastoma


Synonyms

Monstrocellular sarcoma

Definitions

Tumours of the central nervous system
ICD-O-3 topography code: C70, C71 and C72
ICD10: C71
           

A histological variant of glioblastomawith a marked predominance of bizarre, multinucleated giant cells, an occasionally abundant stromal reticulin network and frequent TP53 mutations. Despite the high degree of anaplasia, the giant cell glioblastoma is often more circumscribed and has a prognosis equal to or better than that of the ordinary glioblastoma 1
 
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (Eds.)
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007



.