9250/3 Giant cell tumor of bone, malignant
Giant cell sarcoma of bone
|ICD-O-3 topography code:||C40-C41|
A high grade aggressive bone tumor, usually arising in the end of long bones. The tumor is composed of round or oval mononuclear cells, uniformly distributed osteoclast-like giant cells, and a sarcomatous spindle cell component. Clinical presentation includes pain and edema in the affected area.