8100/0 Trichoepithelioma


Synonyms

Brooke tumor
Epithelioma adenoides cysticum

Definitions

Skin
ICD-O-3 topography code: C44

/span>richoepithelioma (trichoblastoma) is a benign hair follicle neoplasm with trichoblastic differentiation. The tumour typically presents as a small (<1cm; rare cases up to several cm), solitary papule, or, particularly in association with Brooke-Fordyce and Brooke-Spiegler disease, as multiple centrofacial papules or nodules. Trichoepithelioma most frequently affects head and neck, but it may arise on any location bearing hair follicles. Characteristic features of trichoepitheliomas are trichoblastic epithelial components associated with stereotyped stroma. Five histological patterns are distinguished:
> r than being isolated in fenestrations.
Columnar trichoblastoma> gn="left"> LeBoit PE, Burg G, Weedon D, Sarasin A (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours
3rd Edition
IARC Press: Lyon 2005



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Vulva
ICD-O-3 topography code: C51

Trichoepithelioma is a benign hair follicle neoplasm composed of interconnected nests of basaloid cells that form small keratin-containing cysts ("horn cysts").
Trichoepithelioma most frequently affect the head and neck area; in the vulva, the tumour is rare. It presents as a single or multiple cutaneous nodule(s) with overlying skin abnormalities. Recommended treatment is complete excision
2
 
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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