8098/3 Adenoid basal carcinoma


Definitions

Cervix uteri
ICD-O-3 topography code: C53
ICD10: C53
           

Adenoid basal carcinoma is a rare, low-grade variant of basal cell carcinoma characterized by nests and cords of generally well differentiated, small basaloid cells with focal gland formation or, in some cases, central squamous differentiation. The basaloid cell nests are almost always found beneath cervical intraepithelial neoplasia (CIN). They often arise from CIN or from small invasive squamous cell carcinomas.
Adenoid basal carcinoma usually arises in women >50 years of age. Patients are typically asymptomatic; the tumour is often discovered incidentally. Metastases are rare1
 
Tavassoli FA, Devilee P (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs.
3rd Edition
IARC Press: Lyon 2003



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Skin
ICD-O-3 topography code: C44
ICD10: C44
           

Adenoid basal cell carcinoma is a variant of basal cell carcinoma, histologically characterized by adnexal differentiation, including basaloid buds, ductal, sebaceous and trichilemmal elements. The lesions consist of thin strands of basaloid cells forming a reticulate pattern
2
 
LeBoit PE, Burg G, Weedon D, Sarasin A (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours
3rd Edition
IARC Press: Lyon 2005



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Vagina
ICD-O-3 topography code: C52
ICD10: C52
           

A variant of basal cell carcinoma morphologically characterized by the presence of thin strands of basaloid cells forming a reticulate pattern.