8935/1 Stromal tumor, NOS


Definitions

Prostate gland
ICD-O-3 topography code: C61

A benign or malignant neoplasm composed of mesenchymal stromal cells.



Kidney
ICD-O-3 topography code: C64

A benign or malignant neoplasm composed of mesenchymal stromal cells 1
 
Fletcher CDM, Unni KK, Mertens F (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone.
3rd Edition
IARC Press: Lyon 2002



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Metanephric stromal tumour (MST) of the kidney is a rare benign paediatric neoplasm identical to the stromal component of metanephric adenoma. It consists of a lobulated, fibrous, very often cystic mass (mean diameter 5 cm) centred in the renal medulla. MST typically surrounds and entraps renal tubules and blood vessels, resulting in concentric "onionskin" rings or collars around these structures
2
 
Eble JE, Sauter G, Epstein JI, Sesterhenn IA (Eds.)
World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs.
3rd Edition
IARC Press: Lyon 2004



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Affected children usually present with an abdominal mass; haematuria is not uncommon. The mean age at diagnosis is 24 months.